منابع مشابه
Perspective: microarray technology, seeing more than spots.
The publication in the mid-1990s of a new molecular tool, the DNA microarray, has led to a revolution in the way scientists approach the investigation of gene expression and regulation. This technology has made its impact upon many basic scientific disciplines including cancer biology, developmental biology, toxicology, investigation of growth-factor and hormonal signaling, and the applied area...
متن کاملPerspective: Microarray Technology, Seeing More Than Spots
The publication in the mid-1990s of a new molecular tool, the DNA microarray, has led to a revolution in the way scientists approach the investigation of gene expression and regulation. This technology has made its impact upon many basic scientific disciplines including cancer biology, developmental biology, toxicology, investigation of growth-factor and hormonal signaling, and the applied area...
متن کاملSegmentation of Microarray cDNA Spots Using Markov Random Field Modeling
Motivation: Spot segmentation is a critical step in microarray gene expression data
متن کاملImage Analysis for Detecting Faulty Spots from Microarray Images
Microarrays allow the monitoring of thousands of genes simultaneously. Before a measure of gene activity of an organism is obtained, however, many stages in the error-prone manual and automated process have to be performed. Without quality control, the resulting measures may, instead of being estimates of gene activity, be due to noise or systematic variation. We address the problem of detectin...
متن کاملGranulometric Analysis of Spots in DNA Microarray Images
As the topological properties of each spot in DNA microarray images may vary from one another, we employed granulometries to understand the shape-size content contributed due to a significant intensity value within a spot. Analysis was performed on the microarray image that consisted of 240 spots by using concepts from mathematical morphology. In order to find out indices for each spot and to f...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2001
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac012654b